Title: Ph.D., Visiting Scholar.
Professor, Shandong Provincial Key Lab of Ophthalmology, Shandong Eye Institute, Qingdao, China
Address: Dept. of Integrative Medical Biology,
Umeå University, SE-901 87 Umeå, Sweden
Phone: +46 (0)90 786 54 04
Fax: +46 (0)90 786 66 83
Prof. Qingjun Zhou is an international research partner of Prof. Patrik Danielson and a regular visiting scholar at Prof. Danielson's laboratory at Umeå University.
SCIENTIFIC PUBLICATIONS (selection of original work):
Chen J, Lan J, Liu D, Backman LJ, Zhang W, Zhou Q and Danielson P: Ascorbic Acid Promotes the Stemness of Corneal Epithelial Stem/progenitor Cells and Accelerates Epithelial Wound Healing in the Cornea. Stem Cell Transl Med 2017; 6(5); 1356-1365 [Link to article]
Chen J, Chen P, Backman LJ, Zhou Q and Danielson P: Ciliary neurotrophic factor promotes the migration of corneal epithelial stem/progenitor cells by up-regulation of MMPs through the phosphorylation of Akt. Scientific Reports 2016; 6: 25870. [Link to article]
Słoniecka M, Le Roux S, Boman P, Byström B, Zhou Q, and Danielson P: Expression profiles of neuropeptides, neurotransmitters, and their receptors in human keratocytes in vitro and in situ. PLoS ONE 2015; 10(7): e0134157. [Link to article]
Yang L, Di G, Qi X, Qu M, Wang Y, Duan H, Danielson P, Xie L, and Zhou Q: Substance P promotes diabetic corneal epithelial wound healing through molecular mechanisms mediated via the neurokinin-1 receptor. Diabetes 2014; 63; 4262-4274 [Link to article]
Yang L, Qu M, Wang Y, Duan H, Chen P, Wang Y, Shi W, Danielson P¤,
Zhou QJ¤. Trichostatin A inhibits transforming growth factor-β-induced reactive oxygen species accumulation and myofibroblast differentiation via enhanced NF-E2-related factor 2-antioxidant response element signaling. Mol Pharmacol. 2013;83(3):671-80. [Link to article]
(¤=contributed equally to the design and preparation of the manuscript)
Li S, Li B, Jiang H, Wang Y, Qu M, Duan H, Zhou QJ, Shi W. Macrophage depletion impairs corneal wound healing after autologous transplantation in mice. PLoS One. 2013;8(4):e61799.
Zhou QJ, Yang L, Qu M, Wang Y, Chen P, Wang Y, Shi W. Role of senescent fibroblasts on alkali-induced corneal neovascularization. J Cell Physiol. 2012;227(3):1148-56.
Zhou QJ, Yang LL, Wang Y, Qu ML, Wang Y, Chen P, Xie LX, Wang YQ. TGFβ mediated transition of corneal fibroblasts from a proinflammatory state to a profibrotic state through modulation of histone acetylation. J cell phyiol. 2010; 224: 135-43.
Zhou QJ, Chen H, Qu M, Wang Q, Yang L, Xie L. Development of a novel ex vivo model of corneal fungal adherence. Graefes Arch Clin Exp Ophthalmol. 2011;249(5):693-700.
Zhou QJ, Wang Y, Yang LL, Wang Y, Chen P, Wang YQ, Dong XG, Xie LX. Histone deacetylase inhibitors blocked activation and caused senescence of corneal stromal cells. Mol Vis. 2008; 14:2556-2565.
Zhou QJ, Huang YD, Xiang LX, Shao JZ, Zhou GS, Yao H, Dai LC, Lu YL. In vitro differentiation of embryonic stem cells into hepatocytes induced by fibroblast growth factors and bone morphological protein-4. Int J Biochem Cell Biol. 2007;39:1714-21.
Zhou QJ, Xiang LX, Shao JZ, Hu RZ, Lu YL, Yao H, Dai LC. In vitro differentiation of hepatic progenitor cells from mouse embryonic stem cells induced by sodium butyrate. J Cell Biochem. 2007; 100: 29-42.
Zhou QJ, Shao JZ, Xiang LX, Hu RZ, Lu YL, Yao H, Dai LC. Generation of embryoid bodies from mouse embryonic stem cells cultured on STO feeder cells. Cell Biol Int. 2005; 29: 817-825.
Gao Y, Zhou QJ, Qu M, Yang L, Wang Y, Shi W. In vitro culture of human fetal corneal endothelial cells. Graefes Arch Clin Exp Ophthalmol. 2011;249(5):663-9.
Pan X, Wang Y, Zhou QJ, Chen P, Xu Y, Chen H, Xie L. Activation of focal adhesion kinase enhances the adhesion of Fusarium solani to human corneal epithelial cells via the tyrosine-specific protein kinase signaling pathway. Mol Vis. 2011 Mar 5;17:638-46.
Yang LL, Wang Y, Zhou QJ, Chen P, Wang YQ, Wang Y, Liu T, Xie LX. Inhibitory effects of polysaccharide extract from Spirulina platensis on corneal neovascularization Mol Vis. 2009; 15: 1951-61.
Dong XJ, Zhang GR, Zhou QJ, Pan RL, Chen Y, Xiang LX, Shao JZ. Direct hepatic differentiation of mouse embryonic stem cells induced by valproic acid and cytokines. World J Gastroenterol. 2009;15(41):5165-75.
Wang Y, Liu T, Gong H, Zhou QJ, Wang Y, Sun S, Xie L. Gene profiling in murine corneas challenged with Aspergillus fumigatus. Mol Vis. 2007;13:1226-33.
Chen Y, Shao JZ, Xiang LX, Guo J, Zhou QJ, Yao X, Dai LC, Lu YL. Cyclic adenosine 3',5'-monophosphate induces differentiation of mouse embryonic stem cells into cardiomyocytes. Cell Biol Int. 2006; 30: 301-307.
Wang Y, Chen H, Wang Q, Yang LL, Zhou QJ. Comparison of antibiotic activity and corneal epithelial toxicity of moxifloxacin,levofloxacin and gatifloxacin in vitro. Chinese Ophthalmic Research. 2010; 28(6):496-500
Min XJ, Dong XG, Zhou QJ, Liu T, Yin HM, Xie LXExpression of mouse telomerase reverse transcription in a mouse model of oxygen-induced retinopathy. Chinese Journal of Ophthalmology. 2009; 45(3): 199-205
Min XJ, Dong XG, Zhou QJ, Liu T, Yin HM, Xie LX. TERT-siRNA inhibits oxygen-induced retinal neovascularization in mice. Chinese Journal of Ophthalmology. 2009; 45(12): ??
Gao Y, Zhou QJ, Gao ML, Shi WY. Promoting effects of culture medium of corneal stromal cells on proliferation of corneal endothelial cells. Recent Advances in Ophthalmology. 2009; 29(6): 401-404
Min XJ, Zhou QJ, Liu T, Yin HM, Dong XG, Xie LX. Expression and relationship with Bcl-2 of TERT in the mouse model of oxygen-induced retinal neovascularization. Recent Advances in Ophthalmology. 2009; 29(4): 246-253
Hu RZ, Zhou QJ, Shao JZ, Xiang LX, Zhang M, Zhang MC, Lu YL, Yao X, Dai LC. A Novel Method to form Embryoid Bodies Using STO Cells as Feeder Layers. Chinese Journal of Cell Biology. 2005; 27(1): 77-83
Zhou QJ, Xie LX. Progress of stem cells transplantation in the repair of damaged corneal surface. Chinese Journal of Ophthalmology. 2009; 45(7): 658-662
Xie LX, Zhou QJ. Ocular surface reconstruction with cultivated stem cell transplantation: new progresses and challenges. Chinese Journal of Experimental Ophthalmology. 2011; 29(5): 385-389.
Zhou QJ, Shao JZ, Xiang LX, Zhang M, Lu YL, Yao X, Dai LC. Advances in the Research of Differentiation of Embryonic Stem Cells into Hepatocytes. Chinese Journal of Biotechnology. 2005; 21(2): 171-176
Zhou QJ, Hu RZ, Shao JZ, Xiang LX. Notch Signal Transduction and Regulation. Progress in Biochemistry and Biophysics. 2004; 31(3): 198-203
Zhou QJ, Shao JZ, Xiang LX. Progress in Fish Antibacterial Peptide Research. Progress in Biochemistry and Biophysics. 2002; 29(5): 682-685
6. Yang ZF, Shao JZ, Xiang LX, Zhou QJ, Zhang M, Lu YL, Yao X, Dai LC. Side Population Cell: A Novel Stem Cell. Chinese Journal of Cell Biology. 2005; 27(2): 109-112
Liu XM, Xiang LX, Shao JZ, Zhou QJ. The Molecular Mechanisms of Apoptosis Induced by Heavy Metals. Chinese Journal of Cell Biology. 2004; 26(3): 235-240